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Symbol
Name
ID

Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
MGI:99137

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Type II diabetes mellitus	Exocrine pancreatic insufficiency	Pancreatic adenocarcinoma	Goiter	Non-medullary thyroid carcinoma	Papillary thyroid carcinoma
Disease(s) Associated with XRCC1	Diabetes mellitus	Type II diabetes mellitus	Exocrine pancreatic insufficiency	Pancreatic adenocarcinoma	Goiter	Non-medullary thyroid carcinoma	Papillary thyroid carcinoma
coronary artery disease
pancreatic cancer
thyroid gland papillary carcinoma
type 2 diabetes mellitus

Mouse Phenotypes		increased testis apoptosis	abnormal seminiferous tubule morphology	abnormal seminiferous tubule epithelium morphology	decreased testis weight	small testis
Availability	Mouse Genotype
	Alpl^tm1(cre)Nagy/Alpl⁺ Xrcc1^tm1Pmc/Xrcc1^tm1Pmc (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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